Page 75 - ISMCON souvenir 2021

ISMSCON - 2021

(U) among children in India. This paper studies co-occurences of undernutrition outcomes while grouping
together Stunting (S), Wasting (W) and underweight (U) and Anemia (A). Prevalence of No burden,
Single, Dual, triple and quadruple burden are studied for States and regions of India using Data from
India’s DHS 2015-16. Fourteen types of burdens are discovered. Bi-variate analysis, multinomial logistic
regression is performed to study determinants of different burdens of undernutrition. It was found that
21% of children had no burden, 32% had single burden, 23% had dual burden, 20% had triple burden,
whereas 5% had quadruple burden of undernutrition. Quadruple burden varied among Indian States from
0% in Manipur to 9% in Jharkhand. The most prevalent burden of child undernutrition that has been is
found to be of triple burden of Stunting, Underweight and Anemia “SUA”, followed by single burden of
“only anemia”. Anemia is found to have the highest amount of interference with almost every other growth
indicator, whereas stunting is the next dominating one, followed by underweight. It is inferred from bi-
variate analysis that the burden SUA is more associated with undernourished mothers, whereas, “only
anemia” is associated with overnourished or overweight mothers. Similar findings are confirmed from the
regression analysis. Districts are ranked using a composite index of undernutrition. Spatial analysis is
done to identify high risk districts which need multisectoral interventions for the prevalent co-existing form
of undernutrition in that particular area.

OS43: Gallstones and the risk of gallbladder cancer: a systematic
review and meta-analysis

Dr. Prabhaker Mishra , Prof. R.K. Singh , Prof. Sameer Mohindra , Prof. Uttam Singh ,
4
2
3
1
Prof. C.M. Pandey 5
Email: mishrapk79@gmail.com
Contact details for the author (s):
1,4,5Biostatistics and Health Informatics, 2 Surgical Gastroenterology, 3Gastroenterology
1-5Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow - India

Keywords: Gall stones, Gallbladder cancer, Case control study, Systematic review and meta-analysis
Theme of this conference:

Application of Biostatistical Techniques for Summarizing Evidence: Systematic Review & Meta Analysis.
Abstract:
Gallbladder cancer are rare but highly fatal. Although the etiology of Gall bladder cancer (GBC) is poorly
understood, gallstones are considered to be a major risk factor. We will conduct a systematic review and
meta-analysis to examine the associations between presence of gallstone and GBC risk.
Methods: We will search the articles in PUB MED, MEDLINE, Embase and Google scholar. All data
will be independently extracted by two investigators using a standardized data abstraction tool. All the
searched articles to be systematically reviewed and case-control studies published before October
31, 2021 to be included in the study. All the included studies reported appropriate risk estimates and
confidence intervals (CIs) for associations between the presence of Gall sone and risk of GBC to be
presented. Egger test to be performed to assess publication bias.
Results: Results of the individual selected study as well as pooled results to be presented in odds ratios
(ORs) and their 95% Confidence Interval using the Forest plot. The pooled effect to be calculated using
a random or fixed effect model depend upon variability within selected articles.
Conclusions: The presence of Gallstone is associated with an increased risk of Gall bladder cancer
evident from few extracted studies. However, strength and extent of the risk of GBC in presence of gall
stones to be presented after proper extraction of the articles and its final analysis.

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